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KMID : 1189320190130030519
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Asian Spine Journal
2019 Volume.13 No. 3 p.519 ~ p.526
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Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
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Kikanloo Sina Rashidi
Tarpada Sandip Parshottam
Cho Woo-Jin
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Abstract
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Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.
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KEYWORD
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Adolescent, Scoliosis, Adolescent idiopathic scoliosis, Etiology, Cobb angle, Review
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